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1

Crystal structure of the IL-15–IL-15Rα complex, a cytokine-receptor unit presented in trans

Nakamura, Teruya, Toma, Sachiko, Shuto, Tsuyoshi, Kai, Hirofumi, Yamagata, Yuriko, Davis, Simon J, Ikemizu, Shinji, Chirifu, Mami, Hayashi, Chiharu

Journal:

Nature Immunology

Year:

2007

Language:

english

File:

PDF, 596 KB

english, 2007

2

IL-2 and IL-15 signaling complexes: different but the same

Ikemizu, Shinji, Chirifu, Mami, Davis, Simon J

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 865 KB

english, 2012

3

Creation of lysine-deficient mutant lymphotoxin-α with receptor selectivity by using a phage display system

Yasuo Yoshioka, Hikaru Watanabe, Tomohiro Morishige, Xinglei Yao, Shinji Ikemizu, Chioko Nagao, Shandar Ahmad, Kenji Mizuguchi, Shin-ichi Tsunoda, Yasuo Tsutsumi, Yohei Mukai, Naoki Okada, Shinsaku Na

Journal:

Year:

2010

Language:

english

File:

PDF, 772 KB

english, 2010

4

10.1038/35069118

Stamper, Carin C., Zhang, Yan, Tobin, James F., Erbe, David V., Ikemizu, Shinji, Davis, Simon J., Stahl, Mark L., Seehra, Jasbir, Somers, William S., Mosyak, Lidia

Journal:

Year:

2001

Language:

english

File:

PDF, 338 KB

english, 2001

5

10.1038/35079149

Stamper, Carin C., Zhang, Yan, Tobin, James F., Erbe, David V., Ikemizu, Shinji, Davis, Simon J., Stahl, Mark L., Seehra, Jasbir, Somers, William S., Mosyak, Lidia

Journal:

Year:

2001

Language:

english

File:

PDF, 767 KB

english, 2001

6

10.1038/75165

Larsen, Ingrid K., Kasper, Christina, Rasmussen, Hanne, Kastrup, Jette S., Ikemizu, Shinji, Jones, E. Yvonne, Berezin, Vladimir, Bock, Elisabeth

Journal:

Natural Structural Biology

Year:

2000

Language:

english

File:

PDF, 815 KB

english, 2000

7

10.1038/7517

Larsen, Ingrid K., Kasper, Christina, Rasmussen, Hanne, Kastrup, Jette S., Ikemizu, Shinji, Jones, E. Yvonne, Berezin, Vladimir, Bock, Elisabeth

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 75 KB

english, 1999

8

The nature of molecular recognition by T cells

Davis, Simon J., Ikemizu, Shinji, Evans, Edward J., Fugger, Lars, Bakker, Talitha R., van der Merwe, P. Anton

Journal:

Nature Immunology

Year:

2003

Language:

english

File:

PDF, 1.01 MB

english, 2003

9

A functional and structural basis for TCR cross-reactivity in multiple sclerosis

Lang, Heather L.E., Jacobsen, Helle, Ikemizu, Shinji, Andersson, Christina, Harlos, Karl, Madsen, Lars, Hjorth, Peter, Sondergaard, Leif, Svejgaard, Arne, Wucherpfennig, Kai

Journal:

Nature Immunology

Year:

2002

Language:

english

File:

PDF, 401 KB

english, 2002

10

CD2 and the nature of protein interactions mediating cell-cell recognition

Simon J. Davis, Shinji Ikemizu, Martin K. Wild, P. Alton van der Merwe

Journal:

Immunological Reviews

Year:

1998

Language:

english

File:

PDF, 10.41 MB

english, 1998

11

Effects of N-butyldeoxynojirimycin and the Lec3.2.8.1 mutant phenotype on N-glycan processing in Chinese hamster ovary cells: Application to glycoprotein crystallization

Terry D. Butters, Lisa M. Sparks, Karl Harlos, Shinji Ikemizu, David I. Stuart, E. Yvonne Jones, Simon J. Davis

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 228 KB

english, 1999

12

Crystal structure and functional dissection of the cytostatic cytokine oncostatin M

Marc C Deller, Keith R Hudson, Shinji Ikemizu, Jerónimo Bravo, E Yvonne Jones, John K Heath

Journal:

Year:

2000

Language:

english

File:

PDF, 868 KB

english, 2000

13

Optimal site-specific PEGylation of mutant TNF-α improves its antitumor potency

Yasuo Yoshioka, Yasuo Tsutsumi, Shinji Ikemizu, Yoko Yamamoto, Hiroko Shibata, Toshihide Nishibata, Yohei Mukai, Takayuki Okamoto, Madoka Taniai, Maki Kawamura, Yasuhiro Abe, Shinsaku Nakagawa, Satosh

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 388 KB

english, 2004

14

23 Crystal Structure of IL-15/IL-15Rα Complex

Mami Chirifu, Chiharu Hayashi, Teruya Nakamura, Sachiko Toma, Tsuyoshi Shuto, Hirofumi Kai, Yuriko Yamagata, Simon J. Davis, Shinji Ikemizu

Journal:

Year:

2007

Language:

english

File:

PDF, 49 KB

english, 2007

15

235 Structure-function relationship of TNF based on 3D structural analysis of fully active TNFR1-selective TNF mutant

Yohei Mukai, Hiroko Shibata, Teruya Nakamura, Yasuo Yoshioka, Yasuhiro Abe, Tetsuya Nomura, Madoka Taniai, Tsunetaka Ohta, Shinji Ikemizu, Shinsaku Nakagawa, Shin-ichi Tsunoda, Haruhiko Kamada, Yuriko

Journal:

Year:

2008

Language:

english

File:

PDF, 35 KB

english, 2008

16

231 Structure basis for the molecular recognition between IL-15 and its private receptor IL-15Ralpha

Mami Chirifu, Chiharu Hayashi, Teruya Nakamura, Sachiko Toma, Tsuyoshi Shuto, Hirofumi Kai, Yuriko Yamagata, Simon J. Davis, Shinji Ikemizu

Journal:

Year:

2008

Language:

english

File:

PDF, 45 KB

english, 2008

17

Creation of lysine-deficient mutant lymphotoxin-α with receptor selectivity by using phage display

Yasuo Yoshioka, Hikaru Watanabe, Tomohiro Morishige, Xinglei Yao, Shinji Ikemizu, Chioko Nagao, Shandar Ahmad, Kenji Mizuguchi, Yasuo Tsutsumi, Yohei Mukai, Naoki Okada, Shinsaku Nakagawa

Journal:

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

18

Chromium(III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation

Takashi Sato, Yukio Ando, Seiko Susuki, Fumi Mikami, Shinji Ikemizu, Masaaki Nakamura, Ole Suhr, Makoto Anraku, Toshiya Kai, Mary Ann Suico, Tsuyoshi Shuto, Mineyuki Mizuguchi, Yuriko Yamagata, Hirofu

Journal:

Year:

2006

Language:

english

File:

PDF, 167 KB

english, 2006

19

Structure–Function Relationship of Tumor Necrosis Factor (TNF) and Its Receptor Interaction Based on 3D Structural Analysis of a Fully Active TNFR1-Selective TNF Mutant

Yohei Mukai, Hiroko Shibata, Teruya Nakamura, Yasuo Yoshioka, Yasuhiro Abe, Tetsuya Nomura, Madoka Taniai, Tsunetaka Ohta, Shinji Ikemizu, Shinsaku Nakagawa, Shin-ichi Tsunoda, Haruhiko Kamada, Yuriko

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 833 KB

english, 2009

20

Structure and Dimerization of a Soluble Form of B7-1

Shinji Ikemizu, Robert J.C. Gilbert, Janet A. Fennelly, Alison V. Collins, Karl Harlos, E.Yvonne Jones, David I. Stuart, Simon J. Davis

Journal:

Year:

2000

Language:

english

File:

PDF, 435 KB

english, 2000

21

Mutants of lymphotoxin-α with augmented cytotoxic activity via TNFR1 for use in cancer therapy

Morishige, Tomohiro, Yoshioka, Yasuo, Narimatsu, Shogo, Ikemizu, Shinji, Tsunoda, Shin-ichi, Tsutsumi, Yasuo, Mukai, Yohei, Okada, Naoki, Nakagawa, Shinsaku

Journal:

Year:

2013

Language:

english

File:

PDF, 648 KB

english, 2013

22

Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus

Koga, Yukari, Inazato, Miyuki, Nakamura, Teruya, Hashikawa, Chie, Chirifu, Mami, Michi, Asuka, Yamashita, Taku, Toma, Sachiko, Kuniyasu, Akihiko, Ikemizu, Shinji, Nakabeppu, Yusaku, Yamagata, Yuriko

Journal:

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Year:

2013

Language:

english

File:

PDF, 326 KB

english, 2013

23

Impact of antibodies against amyloidogenic transthyretin (ATTR) on phenotypes of patients with familial amyloidotic polyneuropathy (FAP) ATTR Valine30Methionine

Obayashi, Konen, Tasaki, Masayoshi, Jono, Hirofumi, Ueda, Mitsuharu, Shinriki, Satoru, Misumi, Yohei, Yamashita, Taro, Oshima, Toshinori, Nakamura, Teruya, Ikemizu, Shinji, Anan, Intissar, Suhr, Ole,

Journal:

Clinica Chimica Acta

Year:

2013

Language:

english

File:

PDF, 604 KB

english, 2013

24

Crystal Structure of the CD2-Binding Domain of CD58 (Lymphocyte Function-Associated Antigen 3) at 1.8- angstrom Resolution

Shinji Ikemizu, Lisa M. Sparks, P. Anton van der Merwe, Karl Harlos, David I. Stuart, E. Yvonne Jones and Simon J. Davis

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.87 MB

english, 1999

25

The Crystal Structure of the Green Tea Polyphenol (−)-Epigallocatechin Gallate−Transthyretin Complex Reveals a Novel Binding Site Distinct from the Thyroxine Binding Site,

Miyata, Masanori, Sato, Takashi, Kugimiya, Miyuki, Sho, Misato, Nakamura, Teruya, Ikemizu, Shinji, Chirifu, Mami, Mizuguchi, Mineyuki, Nabeshima, Yuko, Suwa, Yoshiaki, Morioka, Hiroshi, Arimori, Takao

Journal:

Year:

2010

Language:

english

File:

PDF, 4.74 MB

english, 2010

26

Role of the Glutamic Acid 54 Residue in Transthyretin Stability and Thyroxine Binding ,

Miyata, Masanori, Sato, Takashi, Mizuguchi, Mineyuki, Nakamura, Teruya, Ikemizu, Shinji, Nabeshima, Yuko, Susuki, Seiko, Suwa, Yoshiaki, Morioka, Hiroshi, Ando, Yukio, Suico, Mary Ann, Shuto, Tsuyoshi

Journal:

Year:

2010

Language:

english

File:

PDF, 3.75 MB

english, 2010

27

Extraction of Rare Earth Metals Using Liquid Surfactant Membranes Prepared by a Synthesized Surfactant

Uezu, Kazuya, Goto, Masahiro, Irie, Shinji, Ikemizu, Kiyoshi, Nakashio, Fumiyuki

Journal:

Separation Science and Technology

Year:

1995

Language:

english

File:

PDF, 708 KB

english, 1995

28

Functional and Structural Effects of Mutagenic Replacement of Asn37 at Subsite F on the Lysozyme-catalyzed Reaction

KAWAMURA, Shunsuke, ETO, Masashi, IMOTO, Taiji, IKEMIZU, Shinji, ARAKI, Tomohiro, TORIKATA, Takao

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2004

Language:

english

File:

PDF, 173 KB

english, 2004

29

Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity

Waz, Shaimaa, Nakamura, Teruya, Hirata, Keisuke, Koga-Ogawa, Yukari, Chirifu, Mami, Arimori, Takao, Tamada, Taro, Ikemizu, Shinji, Nakabeppu, Yusaku, Yamagata, Yuriko

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 3.17 MB

english, 2017

30

A Molecular and Preclinical Comparison of the PD-1 targeted T cell Checkpoint Inhibitors Nivolumab and Pembrolizumab

Fessas, Petros, Lee, Hassal, Ikemizu, Shinji, Janowitz, Tobias

Journal:

Seminars in Oncology

Year:

2017

Language:

english

File:

PDF, 939 KB

english, 2017

31

Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R

Kojima, Toshiyuki, Tsuchiya, Kiichiro, Ikemizu, Shinji, Yoshikawa, Soichiro, Yamanishi, Yoshinori, Watanabe, Mamoru, Karasuyama, Hajime

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.59 MB

english, 2016

32

3P022 Crystal structure of 8-oxo-dATP-hMTH1 complex reveals a diversity of substrate recognition by hMTH1(Proteins-structure and structure-function relationship,Poster Presentations)

Nakamura, Teruya, Arimori, Takao, Ikemizu, Shinji, Shirakawa, Masahiro, Nakabeppu, Yusaku, Yamagata, Yuriko

Journal:

Seibutsu Butsuri

Year:

2007

File:

PDF, 265 KB

2007

33

Structural Biology in Immunology || Principles of Protein Recognition by Small T-Cell Adhesion Proteins and Costimulatory Receptors

Ikemizu, Shinji

Year:

2018

Language:

english

File:

PDF, 2.87 MB

english, 2018

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